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Patients with inflammatory bowel disease, diverticular disease, haemorrhoids, recent colorectal surgery, cardiovascular conditions, pregnancy, severe renal or cardiac impairment, coagulopathy, or recent pelvic radiotherapy face heightened risks

Tirzepatide reduces hunger signals, but it does not create weight loss if calorie intake remains at maintenance levels

"They improve quality of life for everybody." However, like all medications, GLP-1 drugs come with potential side effects

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Given the characteristics of short-lived free radical species, which are challenging to confirm as transferring between cells through gap junctions after APAP overdose, we employed a thioacetamide-induced hepatotoxicity model